Advancements in the prevention and treatment of benign prostatic hyperplasia, with particular emphasis on fireweed (Epilobium angustifolium L.) and nettle (Urtica dioica L.). A review.

Prostate enlargement, medically termed as benign prostatic hyperplasia (BPH), is a prevalent and frequently troublesome issue affecting older men. Research suggests that over 50% of males in their 60s may encounter symptoms associated with BPH. While BPH doesn't pose an immediate threat to life, its implications on urinary function can substantially diminish a man's quality of life. The etiology of BPH involves complex hormonal and inflammatory mechanisms, leading to prostatic enlargement and obstructive symptoms. Traditional management strategies such as α -blockers and 5- α reductase inhibitors offer symptomatic relief but may be associated with adverse effects. In recent years, natural compounds have gained attention for their potential efficacy and safety profiles in managing prostate enlargement. This article reviews recent advancements in the prevention and treatment of BPH, with a particular emphasis on the utilization of herbal remedies, namely fireweed (Epilobium angustifolium L.) and nettle (Urtica dioica L.). The research for this review was conducted using databases PubMed, Scopus, and Google Scholar to gather relevant studies and findings.