Indicators of antioxidant activity in idiopathic infertility: A cohort study

Objective: to assess the level of markers of antioxidant protection in women with infertility of unknown origin in comparison with women who gave birth to at least one living child. Material and methods. A comparative cohort retrospective study was conducted, which included 52 women with infertility of unknown origin and 85 women who do not suffer from infertility. In the course of the work, standard biochemical parameters, antioxidant and peroxidase activity were studied. Results. In women with infertility of unknown origin, the total antioxidant activity is more pronounced (2.21±0.312 and 1.97±0.312 ng/ml; p<0.001), however, a low level of peroxidase activity was found (11.6±3.96 and 13.4±6.67%; p<0.001). Conclusion. In our study, it was found that in women with infertility of unknown origin, the level of total antioxidant capacity of serum is higher than in women who have realized their reproductive function, while peroxidase activity is less pronounced.