Peculiarities of extended gynecological examination data in women with recurrent vulvovaginal candidiasis

The aim of the study - to determine the features of extended gynecological examination in patients with recurrent vulvovaginal candidiasis (RVVC): data from gynecological history, examination, colposcopy, cytological and histological examination to increase the effectiveness of prevention of recurrences in these patients. Materials and methods. A prospective study and clinical-statistical analysis of gynecological history, examination, colposcopy, cytological and histological examination in patients with RVVC was carried out. The main group (MG) consisted of 70 women of reproductive age with RVVC and 40 healthy women of reproductive age, who made up the control group (CG). Results. The most frequent complaint was itching in the vagina - in 32 (45.7%) and itching in the area of the external genitalia, which bothered 29 (41.4%) patients; complaints of dysuric disorders in 19 (27.1%) patients became the reason for an earlier visit, usually to a urologist; dyspareunia occurred in 24 (34.3%) patients. Cervical ectopy with signs of exocervicitis and endocervicitis was found in 20 (28.6%) patients with RVVC; an atypical transformation zone was noted in 15 (21.4%) and was represented by an acetowhite epithelium with clear contours in the transformation zone in 37 (52.8%) p<0.05. At the same time, acetobilious epithelium with punctation was found in 19 (27.1%) patients, acetobilious epithelium with mosaic in 12 (17.1%), simultaneously with punctuation and mosaic in 6 (8.6%) patients. In CG, ectopy without signs of exo- and endocervicitis was observed in 7 (17.5%) patients. A rather high percentage of CIN attracts attention - in 37 (52.8%) of 70 women of MG: of them, CIN I - in 26 (37.1%) women, CIN II - in 9 (12.8%) patients, CIN III - in 2 (2.9%) patients. Conclusions. Subjectively, RVVC was characterized by mild clinical symptoms, at the same time marked inflammatory changes in the lower parts of the genital tract with involvement in the pathological process of the cervix. Every third patient had dysuric disorders against the background of chronic inflammatory diseases of the pelvic organs, which are present in the anamnesis. In most patients, the long recurrent course of the disease was accompanied by psychosomatic disorders, emotional lability. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author.