Taxodin A, a Cytotoxic C₃₀ Terpenoid from Taxodium mucronatum with a Unique Skeleton

Taxodin A ( 1 ), a unique C 30 terpenoid featuring an unprecedented skeleton composed of an abietane‐type diterpene and a menthane‐type monoterpene, was obtained from the leaves and branches of Taxodium mucronatum . The structure and absolute configuration of compound 1 was unequivocally established by the combination of extensive spectroscopic analyses and X‐ray single‐crystal diffraction analysis. Compound 1 exhibited potent cytotoxic activities against A549, SMMC‐7721, MDA‐MB‐231, and SW480 cell lines with IC 50 values of 15.35±0.73, 8.49±0.35, 17.53±0.79, 18.93±0.60 μM, respectively.