Inflammatory bowel diseases (IBD) are characterized by factors such as distorted expression of inflammatory cytokines, dysfunction in the epithelial and mucosal barriers, and dysbiosis of the intestinal flora. 1 The disease itself not only induces morbidity but also complicates treatments, including surgical interventions.The associated immunosuppression, inflammation, and dysbiosis may contribute to abnormal wound healing, further complicating the postoperative course. 2 In Crohn's disease (CD), rates of anastomotic leakage (AL) can reach up to 23%, 3-6 underscoring the challenges in managing these patients.
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Cira et al. (2024) studied this question.
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