A rare case of an aggressive submandibular gland cancer revealed by a parietal-pleural metastasis: Case report and literature review

Around 10% of all salivary gland tumors are located in the sub-mandibular gland, with a high rate of malignant tumors. Mucoepidermoid carcinoma “MCE” represent 13 % of all sub-mandibular gland tumor and is reported to have an aggressive behavior and the most difficult to treat. The purpose of this article is to report a case of 60-year-old patient diagnosed with a high grade mucoepidermoid carcinoma of sub-mandibular gland revealed by a parietal-pleural metastasis in whom a surgical, radiotherapy and chemotherapy treatment has been adapted, and by a literature review we will describe the clinical, histological, therapeutic features and the prognostic factors of this rare and aggressive histological type of sub-mandibular gland.