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March 27, 2024ACS Infectious Diseases

ADAMTS5 Promotes Permeability of the Blood-Brain Barrier during Treponema pallidum Subspecies pallidum Invading the Central Nervous System

Zuoxi Chen Fangzhi Du Ruihua Zhang Qingyun Wu Zhiyu Lu Ruili Zhang Qianqiu Wang

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Abstract

The pathogenesis of neurosyphilis remains unclear. A previous study found a noteworthy up-regulation of a disintegrin and metalloproteinase with thrombospondin type 1 motif 5 (ADAMTS5) gene in human brain microvascular endothelial cells cocultured with

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Chen et al. (2024) studied this question.

synapsesocial.com/papers/68e72200b6db64358769b8ec https://doi.org/10.1021/acsinfecdis.3c00664

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