Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement—the ARISE Study and ARISE Registry Data

Alexander Horke; I. Tudorache; Günther Laufer; Martin Andreas; José Luís Pomar; Daniel Pereda; Eduard Quintana; Marta Sitges; Bart Meyns; Filip Rega; Mark G. Hazekamp; Robert Cesnjevar; Martin Schmiady; John Pepper; Ulrich Rosendahl; Artur Lichtenberg; Dmytro Stadnik; Ramadan Jashari; Dietmar Boethig; Dmitry Bobylev; M. Avşar; Arjang Ruhparwar; Axel Haverich; Serghei Cebotari; Samir Sarikouch

doi:10.1093/ejcts/ezae121

Key Points

Decellularized aortic homografts serve as a viable alternative for aortic valve replacement, providing crucial intermediate follow-up data in young patient cohorts.
Prospective single-arm trial evaluations across Europe track five-year clinical performance, utilizing structured data from the ARISE study alongside registry records.
Long-term decellularized allograft assessments support expanding surgical valve options, offering essential durability benchmarks for young individuals facing surgery.

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Implication

Prospective single-arm trial reports five-year outcomes of decellularized allografts in young patients, highlighting durability for aortic valve replacement.

Abstract

Decellularized aortic homografts (DAH) were introduced as a new option for aortic valve replacement for young patients.

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Horke et al. (2024) studied this question.

synapsesocial.com/papers/68e72435b6db64358769e039 https://doi.org/10.1093/ejcts/ezae121

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Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement—the ARISE Study and ARISE Registry Data

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement—the ARISE Study and ARISE Registry Data

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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