Carcinoid crisis induced by radioligand therapy: a rare but life-threatening complication in patient with neuroendocrine tumor

Carcinoid crisis (CC) is a rare but potentially life-threatening complication that may occur in patients with neuroendocrine tumor (NET). The pathophysiology of CC involves the sudden, massive release of vasoactive substances. This article presents a unique case study of a patient with a disseminated NET of the pancreas, who developed CC after radioligand therapy (RLT). Despite its rarity, awareness of CC as a potential severe complication of RLT is essential for timely and effective management and better prognosis for affected patients.