Case report demonstrates digital gangrene presenting in early systemic lupus erythematosus without antiphospholipid syndrome, highlighting uncommon multiorgan manifestations.
Systemic lupus erythematosus (SLE) is a multisystem disorder presenting with a myriad of presentations including skin manifestations.However, digital gangrene, despite being sporadically reported in various populations, is a rare presentation, especially in relatively early disease and in absence of antiphospholipid syndrome (APS).A case of digital gangrene in a woman leading up to a diagnosis of SLE with multiorgan involvement in the absence of antiphospholipid syndrome is reported here.She was later diagnosed with SLE, lupus nephritis, skin vasculitis with Libman-Sacks endocarditis, and responded well to conservative therapy.
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Sharma et al. (2024) studied this question.
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