Fat embolism syndrome (FES) is defined as the presence of fat particles (i.e., > 100 particles per mm2) in the blood circulation that result in symptoms and/or organ failure. FES could result from mechanical causes, trauma or sepsis and, even if very rare, is a fatal disease that develops within 12-72 hours. FES manifestations can vary from mild cognitive changes to coma and even cerebral edema and brain death.
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Adriano et al. (2024) studied this question.
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