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March 22, 2024Cancer Research

Abstract 2382: KY-CLC-mouse: a common light chain bispecific antibody discovery platform

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Authors

HPHao PengGWGuojin WuFHFeng Hao

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Cite This Study

Peng et al. (2024) studied this question.

synapsesocial.com/papers/68e72e2fb6db6435876a7967https://doi.org/10.1158/1538-7445.am2024-2382
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 6361: KY-HC-mouse: A low-cost and rapid nanobody discovery platform2024
  2. 2Abstract 5851: (Common-light-chain-antibody+nano-body) × multi-matrix-immunization platform facilitates the development of antitumor multispecific antibody drugs2026
  3. 3Abstract 5391: A versatile KY-HC-mouse™nanobody platform enabling tumor-anchored, conditionally active 4-1BB bispecific antibodies2026
  4. 4Abstract LB052: Unlocking the Full Human Antibody Repertoire: Novel Humanized Antibody Mouse Models with Fully Humanized Lambda Chains and Diversified Genetic Backgrounds2026
  5. 5An Engineered Mouse Model That Generates a Diverse Repertoire of Endogenous, High-Affinity Common Light Chain Antibodies2024 · 1 citations