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March 22, 2024Cancer Research

Abstract 1591: Hepatocytes compensate for the loss of PHGDH in pancreatic cancer cells during liver metastasis

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Authors

KGKoelina GangulyKYKeisuke YamamotoJEJoel Encarnacion-Rosado

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Ganguly et al. (2024) studied this question.

synapsesocial.com/papers/68e72e34b6db6435876a7c94https://doi.org/10.1158/1538-7445.am2024-1591
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hepatocytes promote liver metastasis of pancreatic cancer by providing serine2026
  2. 2Abstract 1592: Single-cell transcriptomics reveals unique stromal and metabolic heterogeneity in liver metastatic pancreatic cancer2024
  3. 3Abstract A081: Dissecting the Tumor–Immune Landscape of PDAC Liver Metastases to Identify Candidate Drivers of Immune Evasion and Metastatic Outgrowth2025
  4. 4Abstract 1384: Highly metastatic PDAC adopts mesenchymal morphology and spatially coordinates endothelial cells with macrophages2024
  5. 5PHGDH-High Dormant Tumor Cells Evade Immunity and Drive Metastasis2026