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March 22, 2024Cancer Research

Abstract 6664: In situ vaccination with hyper-interferon sensitive influenza induces adaptive immune response and sensitizes murine non-small cell lung cancer to PD-1 blockade

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Authors

RSRamin Salehi‐RadNational Institutes of HealthYDYushen DuUniversity of California, Los AngelesTZTianhao ZhangUnion Hospital

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Salehi‐Rad et al. (2024) studied this question.

synapsesocial.com/papers/68e72e37b6db6435876a7e85https://doi.org/10.1158/1538-7445.am2024-6664
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyper-Interferon Sensitive influenza induces adaptive immune responses and overcomes resistance to anti-PD-1 in murine non-small cell lung cancer2024 · 6 citations
  2. 2Abstract 6751: <i>In situ</i> vaccination with <i>Flt3l</i> gene modified CD103+ type 1 conventional dendritic cells synergizes with anti-PD-1 checkpoint blockade in murine models of non-small cell lung cancer2024
  3. 3Abstract 4365: Pre-existing immunity boosts therapeutic efficacy of oncolytic influenza a virus in the presence and absence of neutralizing antibodies2026
  4. 4Abstract A030: Reprogramming the SCLC tumor microenvironment to enhance immunotherapy response2026
  5. 5Abstract A052: Safety, immunogenicity and resistance of <i>in situ</i> Immunomodulation with CDX-301, radiotherapy, CDX-1140, and Poly-ICLC in patients with unresectable and metastatic solid tumors: a phase 1 trial2026