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March 21, 2024World Journal of Oncology36 citationsOpen Access

High Ki67 Gene Expression Is Associated With Aggressive Phenotype in Hepatocellular Carcinoma

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VRVicente Ramos‐SantillanUniversity of DenverMOMasanori OshiYokohama City UniversityENErek NelsonRoswell Park Comprehensive Cancer Center

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Abstract

Hepatocellular carcinoma (HCC) with high Ki67 protein expression, the most commonly used cell proliferation marker, is associated with an aggressive biologic phenotype; however, conventional immunostaining is hampered by variability in institutional protocol, specific antibody probe, and by assessor subjectivity. To this end, we hypothesized that Ki67 gene (

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Ramos‐Santillan et al. (2024) studied this question.

synapsesocial.com/papers/68e72f63b6db6435876a941dhttps://doi.org/10.14740/wjon1751
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