We note that infinitely many irreducible, closed, simply connected 4-manifolds, with prescribed signature and spin type, admit perfect Morse functions, i.e. they can be given handle decompositions without 1- and 3-handles. In particular, there are many such 4-manifolds homeomorphic but not diffeomorphic to the standard 4-manifolds # m (S^2 x S^2) and # n (CP^2 # -CP^2), respectively, which answers Problem 4.91 on Kirby's 1997 list.
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R. İnanç Baykur (2024) studied this question.
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