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March 20, 2024Open Access

Atherosclerosis and Bidirectional Relationship between Cancer and Cardiovascular Disease: From Bench to Bedside—Part 1

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Authors

GGGiuseppina GallucciFTFabio Maria TurazzaAIAlessandro Inno

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Overview

Review demonstrates bidirectional mechanisms connecting atherosclerosis and cancer in clinical populations, highlighting translational pathways for precision cardiology.

Key Points

  • Atherosclerosis and cancer exhibit a bidirectional relationship driven by shared chronic inflammation, and lipid-rich plaques actively accelerate cardiovascular disease progression.
  • Review of translational data highlights shared exposomes between conditions, while oncologic studies on cardiotoxicity uncover crucial overlapping pathways in vascular biology.
  • Highlights that integrating oncologic cardiotoxicity findings may inform precision cardiology, offering cross-disciplinary therapeutic strategies to enhance clinical cardioncology.

Cite This Study

Gallucci et al. (2024) studied this question.

synapsesocial.com/papers/68e732bfb6db6435876ac026https://doi.org/10.20944/preprints202403.1185.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Atherosclerosis and the Bidirectional Relationship between Cancer and Cardiovascular Disease: From Bench to Bedside—Part 12024 · 26 citations
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  3. 3Molecular and cellular crosstalk between atherosclerosis and cancer: Mechanistic insights and therapeutic opportunities2026
  4. 4Atherosclerotic Cardiovascular Disease and Cancer2026 · 3 citations
  5. 5Reciprocal Mechanisms Linking Cancer and Cardiovascular Disease: Emerging Paradigms in Onco-Cardiology2026