Chitosan Based Biopatches Impregnated with Amaranthus Spinosus Herbal Drug for Wound Healing Application

Wound healing is a process in which the body repairs and restores damaged or injured tissue to its normal function and structure. This complex and dynamic process involves several stages and cellular events. Supporting the natural wound healing process and promoting optimal healing requires providing proper wound care, including cleaning the wound, keeping it protected and moist, managing underlying health conditions, and addressing any complications that may arise. Therefore it is essential to develop bio patches with necessary wound healing properties [1], [2]. This article highlights chitosan's properties, making it an ideal choice for wound healing. It presents a comprehensive review of Chitosan-based bio patches impregnated with herbal drugs as a novel approach in wound care. Chitosan, a biopolymer derived from chitin, possesses biocompatibility, biodegradability, and antimicrobial properties [15]. Herbal drugs, derived from various species, are known for their wound healing properties, including anti-inflammatory, antimicrobial, and antioxidant effects [3], [11]. Silver nitrate nanoparticles, with their antimicrobial properties and ability to stimulate cell proliferation, have shown promise in wound healing [9]. Incorporating these nanoparticles into wound dressings and coatings can promote faster wound closure and reduce the risk of infections. A well-designed bio patch, by promoting tissue regeneration and reducing inflammation, can help minimize the formation of excessive scar tissue and reduce pain associated with the wound site. The process protein extraction essential for fabrication of such biopatch is shown in figure 1. It creates a barrier that protects the wound from external contaminants and promotes tissue regeneration, providing a conducive environment for wound healing.