An unusual localization of an Abrikossoff tumor

Abrikossoff’s tumor, also known as Granular Cell Tumor (GCT), is a rare benign neoplasm commonly found in the cervicofacial region, particularly the oral cavity. Here, we present a case of GCT occurring in an atypical location on the left flank of a 43-year-old patient. The lesion presented as an erythematous ovoid nodule with central ulceration, accompanied by white structures and polymorphic vascularization on dermoscopy. Initially considered as Darrier-Ferrand’s dermatofibrosarcoma, histopathological examination of a cutaneous biopsy revealed granular cells and eosinophils in the dermis, suggestive of GCT. Immunohistochemical analysis confirmed the diagnosis, expressing S100 protein and CD68. Complete surgical excision with safety margins was performed, with no recurrence observed after 1 year of follow-up. This case highlights the importance of considering GCT in the differential diagnosis of flank lesions and emphasizes the need for clinicians to remain vigilant for uncommon presentations of this rare tumor.