Objective: This review explores the evolving landscape of therapeutic interventions for chronic ulcers, emphasizing the importance of understanding etiology and optimizing patient outcomes in dermatological therapy. Background: Chronic ulcers present a significant challenge in dermatological therapy, necessitating a comprehensive understanding of their etiology for effective treatment. While addressing underlying pathology is crucial, local therapy, exceptionally moist wound healing, plays a pivotal role in managing these wounds. Scope: Current treatment strategies prioritize moist wound healing and encompass various modalities to promote tissue repair and mitigate complications. This review explores established practices such as cleaning, debridement, infection control, and emerging techniques, including biological skin substitutes, growth factors, laser therapy, hyperbaric oxygenation, electrical stimulation, and negative pressure dressings. Critical Interventions: The review highlights traditional and novel approaches to managing chronic ulcers, providing insights into optimizing patient outcomes and advancing dermatological condition management. Significance: Understanding the evolving landscape of therapeutic interventions for chronic ulcers is essential for dermatologists, healthcare professionals, and researchers. This review aims to provide valuable insights for optimizing patient care and improving treatment outcomes by examining established and emerging techniques.
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Hazoor et al. (2024) studied this question.
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