• Liquid biopsy is a promising diagnostic and prognostic tool for HNSCC. • Exosomes in biological fluids offer a comprehensive composition of DNA, RNA, lipids, metabolites, and cell surface proteins, contributing to a holistic understanding of the disease. • LncRNAs play an important role in tumour metastasis thereby serving as a source for liquid biopsy. • Minimally invasive liquid biopsy of Exosomal lncRNAs provides a safer and more feasible prognostic marker.
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Sindya et al. (2024) studied this question.
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