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March 15, 2024Organic LettersOpen Access

Synthesis of Bufadienolide Cinobufagin via Late-Stage Singlet Oxygen Oxidation/Rearrangement Approach

Colin Tichvon Eugene Zviagin Zoey J. Surma Pavel Nagorny

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Abstract

This manuscript describes a concise synthesis of cinobufagin, a natural steroid of the bufadienolide family, from readily available dehydroepiandrosterone (DHEA), as well as its α5-epimer derived from 3-

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Cite This Study

Tichvon et al. (2024) studied this question.

synapsesocial.com/papers/68e73cccb6db6435876b6736 https://doi.org/10.1021/acs.orglett.4c00625

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