Pulmonary Blastomycosis in Children With Relapse Acute Lymphoblastic Leukemia: A Case Report

Background: Blastomycosis is rare fungal infection in Indonesia, South East Asia. However, this infection can be found in immunocompromised children. Host susceptibility plays a role in pathogenesis. Children with acute lymphoblastic leukemia (ALL) who get chemotherapy is immunocompromised and prone to fungal infection. Pulmonary blastomycosis often misdiagnosed with Community Acquired Pneumonia (CAP) or Pneumocystis pneumonia (PCP) in patient with ALL. We should be aware of this infection because it may cause morbidity and mortality of patient with severe immunosupression. We present a case of 5 year-old boy who came to the hospital with shortness of br Methods: eath. This patient was also diagnosed as relapse acute lymphoblastic leukemia and was treated with 3rd week of induction phase of chemotherapy of ALL High Risk (HR) protocol. Culture of the organism was performed and showed Blast Result: omyces dermatitidis. We should be aware of the possibility of pulmonary blastomycosis infection in patient Conclusion: with ALL who get chemotherapy. Careful consideration and early detection of this infection may help to improve survival.