Photobiomodulation therapy for the management of oral mucositis: a clinical case

Oral Mucositis (OM) is an inflammatory alteration of the mucosa primarily due to the damage resulting of cytotoxic effects of radiotherapy, chemotherapy, bone marrow transplantation and stem cell transplantation. The use of photobiomodulation (PBM) therapy for oral mucositis is intended to reduce or prevent lesions from manifesting. However, there is no consensus on the treatment dosimetry based on higher treatment success rates, and no exact cause of treatment success or failure has been found for large groups of patients. Therefore, optimizing treatment protocols and investigating causes affecting treatment outcomes is of paramount importance to decrease pain, hospitalization time, death rates of oncological patients while giving them improved quality of life via nutrition without pain. This case study shows a successful example of the treatment outcome of a new PBM therapy protocol for OM where we concluded that PBM therapy can be used as a potentially effective preventive and curative treatment of OM.