Introduction: Previously, we have shown that hyponatremia (HypoNa) impairs bone tissue to a similar extent as estrogen deficiency and that both factors have a synergistic adverse effect on bone healing.The present study investigated whether HypoNa worsens the effect of estrogen depletion on bone in an ovariectomized rat model for postmenopausal osteoporosis.
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Komrakova et al. (2024) studied this question.
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