March 12, 2024The Lancet Global HealthOpen Access

Point-of-care testing and treatment of sexually transmitted and genital infections to improve birth outcomes in high-burden, low-resource settings (WANTAIM): a pragmatic cluster randomised crossover trial in Papua New Guinea

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Antenatal point-of-care testing for bacterial vaginosis and curable infections showed no reduction in preterm birth or low birthweight, with a risk ratio of 1.06 across 4,297 infants.
A pragmatic cluster randomised crossover trial across ten primary facilities evaluated point-of-care testing for Trichomonas vaginalis and genital infections among 4,526 pregnant women.
Findings highlight that routine point-of-care testing did not alter adverse birth outcomes overall, though women with Neisseria gonorrhoeae experienced a substantial outcome reduction.

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Implication

Randomized cluster crossover trial finds antenatal point-of-care testing and treatment of genital infections does not reduce adverse birth outcomes, indicating standard syndromic care remains...

Cite This Study

Riddell et al. (2024) studied this question.

synapsesocial.com/papers/68e745a8b6db6435876be8dc https://doi.org/10.1016/s2214-109x(24)00004-4

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Implication

Randomized cluster crossover trial finds antenatal point-of-care testing and treatment of genital infections does not reduce adverse birth outcomes, indicating standard syndromic care remains...

Point-of-care testing and treatment of sexually transmitted and genital infections to improve birth outcomes in high-burden, low-resource settings (WANTAIM): a pragmatic cluster randomised crossover trial in Papua New Guinea

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Discussion

Implication

Cite This Study

Point-of-care testing and treatment of sexually transmitted and genital infections to improve birth outcomes in high-burden, low-resource settings (WANTAIM): a pragmatic cluster randomised crossover trial in Papua New Guinea

Key Points

Discussion

Implication

Cite This Study

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