Novel surface plasmon resonance (SPR)-based biosensor for pathogenic bacteria detection (PathoBactD)

This paper presents a novel approach for pathogenic bacteria detection (PathoBactD) through the utilization of a surface plasmon resonance (SPR)-based biosensor. The sensor consists of a BK7 prism coated with silver (Ag), barium titanate (BaTiO₃), and molybdenum diselenide (MoSe₂) in the Kretschmann arrangement. The proposed SPR-based biological sensor incorporates the concept of attenuated total reflection (ATR) for accurate measurements. Various performance characteristics of the sensor, including sensitivity, figure of merit (FoM), signal-to-noise ratio (SNR), detection accuracy, and quality factor, have been thoroughly analyzed. The integration of BaTiO₃ significantly enhances the sensor's capability for PathoBactD. To evaluate the impact of the BaTiO₃ layer on the performance parameters of the MoSe₂-based SPR biological sensor, a theoretical model employing the angular interrogation technique has been developed.