Wavelength and resolution dependency of dynamic optical coherence tomography

We investigate wavelength and resolution dependency on dynamic optical coherence tomography (D-OCT) signal using two OCT systems. One is 840-nm spectral domain OCT. The other is 1310-nm swept-source OCT. We kept the resolution roughly the same between the two systems by computationally reducing the axial resolution of 840-nm system. In addition, we performed numerical simulation by modeling the intracellular scatterer dynamics by a diffusion. Experimental results showed that longer wavelengths correspond to lower D-OCT, while lower resolutions lead to slightly lower D-OCT. Simulation results confirm the wavelength dependency of D-OCT, with resolution variations having non-significant impact.