We demonstrate a single-shot full-field reflection-mode off-axis quantitative phase microscopy with temporal focusing. The new imaging system is capable of achieving diffraction-limited optical sectioning quantitative phase imaging without any spatial or angular multiplexing. It has high potential to achieve ultrafast imaging with camera-limited frame rate. We show that the QPM can measure the depth-dependent intracellular scattering dynamics of cells and reveals 3D structure of tissues with different phenotypes at sub-cellular resolution.
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Lin et al. (2024) studied this question.
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