Nano MgCuAl2O5: Synthesis by Sol-Gel Auto-Combustion Process, Characterization and Reusable Heterogeneous Catalyst for the Hantzsch 1,4-Dihydropyridine Reaction

For the first time, MgCuAl2O5 heterogeneous nanocatalysts were prepared by sol-gel auto-combustion method, which displayed great yield and suitable activity for the preparation of 1,4-DHP derivatives with high efficiency in green solvent ethanol/water (1:1) at 80 °C under one pot condition. The synthesis materials were separated in short reaction times with excellent yield (80-95) %. Moreover, the synthesized nanocatalyst was easily retrieved and continuously reused for six reactions without a noticeable significant loss of proficiency. The solid catalyst was confirmed by XRD, BET, FTIR, FESEM and EDX, and the substituted 1,4-dihydropyridines were characterized by melting point, 1H and 13C NMR.