Novel coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic and sudden onset of anosmia, has been recognized as a major clinical characteristic of the disease. Metanalysis of 107 studies suggested no objective parameter of severity of COVID-19 with anosmia is established. A study including age and gender matched 101 patients in each group was studied and patients with anosmia has strong association with D-Dimer, IL-6, Ferritin, LDH, Orf1ab gene, CT severity index. Also, better prognosis as compared to non-anosmic covid positive patients as compared to requirement of respiratory assistance. The present study is the first study to attempt to determine cut-offs of elevated levels of Inflammatory biomarkers in the prediction of requirement of respiratory assistance in SARS-CoV2 positive anosmia patients.
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Agrawal et al. (2024) studied this question.
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