Outcome of hepatorenal syndrome - AKI in hepatic care unit in Aswan University Hospital “one year study”

Background;Liver Cirrhosis is a chronic disease characterized by fibrosis and structurally abnormal nodules, representing the final histological change for a variety of chronic liver diseases (1). Cirrhosis is associated with high morbidity and mortality and renal failure is one of the most severe complications (2). Hepatorenal syndrome (HRS-AKI) is a unique type of renal failure that occurs at the late stages of cirrhosis.Aim of the work: To estimate the outcome of HRS - AKI among patients attending Aswan University Hospital in the hepatic care unit for one-year .Patients and methods: This study was a cross-sectional study conducted on 60 patients at the hepatic care unit in Aswan University Hospital, from April 2020 to March 2021.Result: Among the studied cases, there were 22 (36.7%) cases with diabetes, 16 (26.7%) cases with hypertension, 8 (13.3%) with hepatocellular carcinoma, 60 (100%) with ascites, 40 (66.7%) with hepatic encephalopathy, 35 (58.3%) spontaneous bacterial peritonitis and 22 (36.7%) with sepsis. There were 25(41.6%) cases improved and 35 (58.3%) cases not improved.Conclusion: AKI is common in patients with cirrhosis admitted to ICU, associated with significant in-hospital mortality. HRS-AKI was the most common and severe type of AKI in patients with cirrhosis admitted to ICU.