PRES syndrome in the practice of a neurologist: a clinical case

Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic condition that occurs secondarily in response to the inability of the posterior circulation system to respond to acute changes in blood pressure. Hyperperfusion leads to a violation of the blood-brain barrier, resulting in the development of vasogenic edema, more often in the parietal-occipital region.1 This article presents a clinical case of a young patient with the PRES syndrome, after taking large amounts of narcotic and alcoholic substances, and clinically manifested by convulsions and spastic hypertension in all extremities, which led to restriction of the patient's movement. The peculiarity is the persistence of clinical manifestations and the lack of visible effects from treatment. Therefore, given the importance of changes in brain matter and the versatility of clinical manifestations, a clinical case of PRES syndrome in a patient is presented below to improve the awareness of practicing neurologists. The peculiarity of this case is the severity of clinical manifestations and an unfavorable outcome, which is relatively rare in this syndrome.