The Application of Artificial Intelligence in the Research and Development of Traditional Chinese Medicine

Review The Application of Artificial Intelligence in the Research and Development of Traditional Chinese Medicine Zhipeng Ke 1, 2, Minxuan Liu 1, 2, 3, Jing Liu 1, 2, Zhenzhen Su 1, 2, Lu Li 1, 2, Mengyu Qian 1, 2, Xinzhuang Zhang 1, 2, Tuanjie Wang 1, 2, Liang Cao 1, 2, Zhenzhong Wang 1, 2, and Wei Xiao 1, 2, * 1 National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Lianyungang 222106, China 2 Jiangsu Kanion Pharmaceutical Co. , Ltd, Lianyungang 222104, China 3 ‍School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210009, China * Correspondence: xwₖanion@163. com Received: 4 September 2023 Accepted: 4 November 2023 Published: 6 March 2024 Abstract: With the accumulation of data in the pharmaceutical industry and the development of artificial intelligence technology, various artificial intelligence methods have been successfully employed in the drug discovery process. The integration of artificial intelligence in Traditional Chinese medicine has also gained momentum, encompassing quality control of Chinese patent medicines, prescriptions optimization, discovery of effective substances, and prediction of side effects. However, artificial intelligence also faces challenges and limitations in Traditional Chinese medicine development, such as data scarcity and complexity, lack of interdisciplinary professionals, black-box models, etc. Therefore, more research and collaboration are needed to address these issues and explore the best ways to integrate artificial intelligence and Traditional Chinese medicine to improve human health.