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March 5, 2024European Journal of Surgical OncologyOpen Access

Survival associated with the use of one-step nucleic acid amplification (OSNA) to detect sentinel lymph node metastasis in cervical cancer

Nicolò Bizzarri Camilla Fedele Elena Teodorico Camilla Certelli Luigi Pedone Anchora Vittoria Carbone Diana Giannarelli Anna Fagotti Gian Franco Zannoni Michele Valente Denis Querleu Gabriella Ferrandina Giovanni Scambia Francesco Fanfani

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Abstract

Sentinel lymph node (SLN) biopsy is part of surgical treatment of apparent early-stage cervical cancer. SLN is routinely analyzed by ultrastaging and immunohistochemistry. The aim of this study was to assess the survival of patients undergoing SLN analyzed by one-step nucleic acid amplification (OSNA) compared with ultrastaging.

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Cite This Study

Bizzarri et al. (2024) studied this question.

synapsesocial.com/papers/68e75a00b6db6435876d0cce https://doi.org/10.1016/j.ejso.2024.108250

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1One-Step Nucleic Acid Amplification Analysis of Sentinel Lymphatic Nodes in Endometrial Cancer Patients (EU-OSNA): A European Multicenter Diagnostic Accuracy Study.2025 · 1 citations
2768 Non-inferiority study of the OSNA technique with respect to ultrastaging in the sentinel lymph node study in cancer of the initial cervical2024
3One Step Nucleic Acid Amplification (OSNA) Lysate Samples Are Suitable to Establish a Transcriptional Metastatic Signature in Patients with Early Stage Hormone Receptors-Positive Breast CancerOriginal Research · 2022 · 2 citations
4One-step Nucleic Acid Amplification for Detection of Lymph Node Metastasis in Lung CancerOriginal Research · 2013 · 23 citations
5Sentinel Lymph Node Mapping in Lung Cancer: A Pilot Study for the Detection of Micrometastases in Stage I Non-Small Cell Lung Cancer2024 · 3 citations

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Sentinel lymph node detection in gastric cancer using a dual tracer (Superparamagnetic iron oxide and methylene blue): a prospective study with histological and OSNA validation2026
Validation of sentinel lymph node biopsy with completion neck dissection in oral cavity cancer.2025
Sentinel lymph node biopsy versus lymphadenectomy in early-stage cervical cancer: a meta-analysis of oncologic outcomes and surgical morbidity2026

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