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September 16, 2025

Validation of sentinel lymph node biopsy with completion neck dissection in oral cavity cancer.

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Authors

EPErim PamukBTBurçay TellioğluEEErgin Eroğlu

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Overview

Retrospective analysis shows SLNB accuracy in early oral cavity cancer, suggesting its role in lymphatic mapping.

Key Points

  • SLNB shows 100% sensitivity in early-stage oral cavity squamous cell carcinoma, indicating its effectiveness.
  • In advanced tumors, sensitivity and negative predictive value decreased to 55.6% and 60%, with a 44.4% false-negative rate noted.
  • A retrospective cohort analysis involved 57 clinically node-negative oral cavity cancer patients undergoing SLNB.
  • These findings support SLNB's potential in both staging and mapping for patient-specific treatment strategies.

Cite This Study

Pamuk et al. (2025) studied this question.

synapsesocial.com/papers/68c93fe601120bef803badd2https://doi.org/10.1080/00016489.2025.2556821
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sentinel Lymph Node Biopsy for Early-Stage Oral Cavity Cancer: Analysis of Diagnostic Accuracy and False-Negative Cases2026 · 1 citations
  2. 2Sentinel lymph node biopsy in early-stage oral squamous cell carcinoma: A retrospective single-center analysis2024 · 4 citations
  3. 3Diagnostic accuracy of sentinel lymph node biopsy in clinically early-stage (cT1-2N0) oral tongue squamous cell carcinoma: A prospective study2026
  4. 4Sentinel Lymph Node Biopsy (SLNB) for Early-Stage Head and Neck Squamous-Cell Carcinoma of the Tongue: Twenty Years of Experience at I.N.T. “G.Pascale”2024 · 7 citations
  5. 5Sentinel Lymph Node Biopsy Versus Elective Neck Dissection in Carcinoma of the Tongue and Floor of the Mouth2025 · 2 citations