Acute HCV Infection Induced Immune Thrombocytopenia Complicated by Intracerebral Hemorrhage: A Case Report

Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that causes isolated thrombocytopenia. Many viruses have been identified as triggering the autoimmune process, including HIV, HCV, EBV, parvovirus, rubella and measles. However, ITP in association with HCV infection rarely occurs in intial stages when AntiHCV is still nonreactive in rapid test kits. We describe the case of a 45years old otherwise healthy male who presented with acute left sided intracerebral hemorrhage and generalised purpura. Initial labs showed severe thrombocytopenia followed by negative rapid test kit for viral markers including AntiHCV and HBsAg but positive HCV RNA.Learning Points: -1) Acute HCV Infection Can Cause Severe Immune Thrombocytopenia 2) HCV Infection should be ruled out if the HCV antibody test is Non Reactive 3) Intracerebral Hemorrhage is an uncommon presentation in Acute HCV infection associated ITP