Copper and Iron Levels in Wilson's Disease Cases

Wilson's disease is a genetic disorder that prevents elimination of extra copper and causes build-up signs in various organs such as liver, brain, eyes etc. and may cause life-threatening organ damage. The predominant symptoms of this disease manifested as mood change, depression, dark urine or light-colored stool, jaundice, brownish ring around the edge of cornea, tremors, stiff muscles, incoordination etc. The vital role of copper in formation of red blood cells and making immune system healthy. It also act as antioxidant and helps to reduce free radical injuries to cells. Deficiency of copper may cause neurological signs, polyneuropathy such as sensory ataxia i.e. irregular coordination due to proprioceptive loss. Iron role in growth and development, to make hemoglobin, carries oxygen etc. neurodegenerative disorders may occur in iron accumulation in brain and may manifest as dystonia, dyarthria etc. the present study was undertaken to assess the levels of copper and iron.