Highlights from the Literature| March 04 2024 Editors' Selections from Relevant Scientific Publications Author & Article Information Online ISSN: 1940-6215 Print ISSN: 1940-6207 ©2024 American Association for Cancer Research2024American Association for Cancer Research Cancer Prev Res (Phila) (2024) 17 (3): 91. https://doi.org/10.1158/1940-6207.CAPR-17-3-HFL Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record March 4 2024 Citation Editors' Selections from Relevant Scientific Publications. Cancer Prev Res (Phila) 1 March 2024; 17 (3): 91. https://doi.org/10.1158/1940-6207.CAPR-17-3-HFL Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Diabetes drugs by Steven Depolo via The Indian Practitioner Glucagon-like peptide-1 (GLP-1) receptor agonists are type 2 diabetes drugs that can induce considerable weight loss, and this effect may be associated with protection against colorectal cancer. Given that overweight individuals are at heightened risk of developing such malignancies, Wang et al. performed a retrospective analysis of more than 1.2 million diabetes patients to assess the impact of GLP-1 agonists relative to other therapies. They found that overweight diabetic patients taking GLP-1 agonists were significantly less likely to develop colorectal cancer within 15 years of starting treatment, with roughly 50% risk reduction compared to insulin or metformin. A similar pattern was also seen in the larger cohort—although the difference between drugs was not always statistically significant—suggesting that this effect is not exclusively associated with weight loss. Wang L, … Berger NA. JAMA Oncol. 2023 Dec 7:e235573. Physical activity (via... You do not currently have access to this content.
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