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March 4, 2024Blood Cancer Discovery

Abstract P19: Mitohormetic Regulation in Multiple Myeloma: Exploiting Mitochondrial Stress Responses for Therapeutic Gain

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Authors

STSerges P. TsofackUniversity Health NetworkDCDanielle CroucherArtistic Realization TechnologiesBBBenjamin G. BarwickEmory University

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Tsofack et al. (2024) studied this question.

synapsesocial.com/papers/68e75dd0b6db6435876d4d82https://doi.org/10.1158/2643-3249.bcdsymp24-p19
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PSMD3 orchestrates metabolic reprogramming and immunogenic cell death in multiple myeloma2025 · 1 citations
  2. 2Multi-omics reveals immune features in immune and non-immune cells, an IFN-γ/IFN-α-B2M positive feedback loop, and targeted metabolic therapy in multiple myeloma2025
  3. 3NAMPT in macrophages promotes multiple myeloma drug resistance through mitochondrial metabolic reprogramming and modulates immunosuppression via the SIRT1/STAT3/SPP1 axis.2025 · 1 citations
  4. 4Monocyte‐mediated metabolic rewiring via CD31‐CD38 interactions promotes growth and drug‐resistance in multiple myeloma2026
  5. 5Dissecting the multiple myeloma survival niche to improve novel treatment strategies2025