Skeletal fluorosis is an uncommon toxic bone condition marked by the excessive buildup of fluoride in the skeletal structure. The disease manifests as an endemic issue in certain regions of the world and arises from prolonged ingestion or, rarely, inhalation of elevated levels of fluoride. Key imaging features include bilateral patchy bony sclerosis, enthesopathy, ligament, and periosteal bony proliferation, as well as ossification of spinal ligaments. Management of fluorosis generally focuses on symptom treatment.
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Naimi et al. (2024) studied this question.
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