Melorheostosis (Leri’s) Disease: Unique Presentations of Two Cases

The case reports presented in this article outline different presentations of a rare condition of melorheostosis.We present a 52-year-old female patient and a 46-year-old female with classical imaging findings of the condition with multiple imaging studies' pathognomonic "candle wax" appearance.Both patients had presented with the typical symptom of pain and the diagnosis was confirmed radiographically.Both patients presented uniquely with a combination of several features previously identified on case reports.The 52-year-old patient was diagnosed with a polyostotic form in the lower extremities and the 46-year-old patient was diagnosed with the monostatic form in the upper extremity.Patients were eventually treated with conservative management with continued monitoring of the symptoms and disease progression.The cases presented emphasize the importance of imaging studies in the diagnosis and different presentations of the condition, melorheostosis.