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March 1, 2024Diabetes/Metabolism Research and ReviewsOpen Access

Interaction effects of MTHFR C677T and A1298C polymorphisms with maternal glycated haemoglobin levels on adverse birth outcomes

Weixiang Wu Dan Luo Cunwei Ji Fuqiang Diao Lihong Wu Xiaolin Ruan Chunming Gu Mingyong Luo

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Abstract

The role of maternal genetic factors in the association between high glycated haemoglobin (HbA1c) levels and adverse birth outcomes remains unclear.

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Cite This Study

Wu et al. (2024) studied this question.

synapsesocial.com/papers/68e7648eb6db6435876d9dce https://doi.org/10.1002/dmrr.3794

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathiescase-control · 2011 · 65 citations
2Association analysis of MTHFR (C677T, A1298C) and MTRR (A66G) gene polymorphisms on susceptibility to gestational diabetes mellitus in Chinese pregnant women2025 · 1 citations
3Association of <scp>MTHFR</scp> (<scp>C677T</scp>, <scp>A1298C</scp>) and <scp>MTRR A66G</scp> polymorphisms with fatty acids profile and risk of neural tube defects2024 · 3 citations
4B-238 Genotypic Frequency of the C677T and A1298C Variants of the MTHFR Gene in Patients with Infertility and Fetal Loss2025
5C677T and A1298C Polymorphisms of the Methylenetetrahydrofolate Reductase Gene: Incidence and Effect of Combined Genotypes on Plasma Fasting and Post-Methionine Load Homocysteine in Vascular Diseasecross-sectional · 2001 · 187 citations

More related papers

MTHFR variants modify the association between pre-pregnancy BMI and postpartum abnormal glucose tolerance among women with gestational diabetes mellitus2026
Association Between MTHFR Gene Polymorphisms and Subclinical Hypothyroidism in Early Pregnancy: A Retrospective Case-Control Study2026
Association between MTHFR polymorphisms and vitamin D status in infertile women: a mediation analysis2025

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