Association of Overweight and Obesity with Monosymptomatic Nocturnal Enuresis in 5-15 Years Old Children

Background: Monosymptomatic nocturnal enuresis (MNE) has increasingly been reported as a challenging issue for families and children due to its impact on the psychological aspects of children and on reducing their concentration at school the next day. Obesity might serve as a risk factor for voiding dysfunction in children. Our study aimed to evaluate the relationship between excess body mass index (BMI) in children and MNE. Methods and Results: This case-control study included 60 children diagnosed with MNE (the main group [MG]) and 60 children without MNE (the control group [CG]) aged 5-15 years. Proper matching between the two groups concerning age and sex was adopted. Age, weight, family history, and complete medical history were recorded for each participant. In the MG, 18(30%) children had excess BMI, and 42(70%) had normal BMI. In contrast, 9(15%) children in the CG had excess BMI, and 51(85%) children had normal BMI, indicating a statistically significant association between increased BMI and MNE (P=0.049). The frequency of positive family history was significantly higher among the MG than the CG (P=0.0001). The findings of this study showed no significant relationship between gender and a family history of enuresis with excess BMI in children with MNE (P=0.679 and P=0.234, respectively). Conclusion: Obesity and overweight in children have an influence on the development of MNE.