First long-term analysis of survival and clinical outcome in patient-specific instrumentation for total knee arthroplasty: follow-up of a prospective cohort study

method as compared to conventional instrumentation 4,5 .Short to midterm results show similar good clinical outcomes of PSI guided as compared to conventionally instrumented TKAs 4,6,7 .To our knowledge, there is only limited evidence reporting on implant survival and long-term clinical outcomes up to 5 years after a PSI procedure 8 .Additionally, no studies have been performed observing these patients for a follow-up period of over 5 years.Multiple authors emphasized the importance of long-term analysis of clinical outcome and implant survival after PSI TKA 4,6,8 .This is even more relevant given the substantial rise in TKA procedures performed in a younger, and therefore, more active patient population 9,10 .This study is a continuation of previously published articles that evaluated surgical data, radiological alignment, implant survival and clinical outcomes at earlier follow-up moments in a cohort of 184 patients (200 TKAs) who received TKA using PSI 1,12 .