1169 The success of frozen examination and factors influencing success in borderline ovarian tumors

Introduction/Background In the surgical management of Borderline ovarian tumors (BOT), intraoperative frozen section examination plays a crucial role. In our study, we investigated the factors influencing the success and consistency of frozen section examination in the diagnosis of BOT. Methodology The study included patients who underwent surgery at Hacettepe University Hospital and were diagnosed with at least borderline ovarian tumors (BOT) through frozen section examination. Demographic and clinical information was obtained retrospectively. Results A total of 74 patients were included in the study, with a mean age of 41.7 (± 16.09). Patient characteristics are summarized in Table 1. Lymph node dissection was performed in 35 patients (47.3%). Malignant ovarian tumors were detected in 13 patients at final pathology results (17.6%). In the group with the highest rate of BOT diagnosis in frozen section examination, the rate of malignancy detection in the final pathology was 10% (n:1), while in the group with the least BOT diagnosis, this rate was 60% (n:9). This difference was statistically significant (p=0.018). In the group with malignant final pathology, age was found to be statistically significantly higher compared to the group with non-malignant final pathology (p=0,002). However, no significant differences were observed in terms of menopausal status, CA 125, CA 19–9, CA 15–3, CEA levels, tumor size, bilaterality, and the presence of ascites. Conclusion In our study, the rate of detecting borderline ovarian tumors with intraoperative frozen section examination was observed to be consistent with the literature. We observed that the likelihood of ovarian malignancy is higher with increasing age and in cases where at least BOT is diagnosed by frozen section examination. In our opinion, these two conditions may play a role in determining the extent of surgical treatment. Disclosures All authors declare that they have no conflicts of interest.