293 Laparoscopic surgery of endometrial carcinoma with sentinel lymph node biopsy

Introduction/Background Endometrial cancer is the most common carcinoma of the female reproductive organs in developed countries. Lymph node involvement is one of the most important prognostic factors in endometrial cancer. Sentinel lymph node biopsy (SLNB) has been increasingly used as a method to identify lymph node metastases in gynecological malignancies while minimizing the complications associated with extensive lymphadenectomy. The concept of SLN biopsy refers to selective and directed sampling of the first-in-chain lymph nodes that drain from a malignant tumour. The aim of our study is to represent the outcome of laparoscopic surgery in terms of the amount of positive lymph nodes retrieved, postoperative complications and morbidity, survival rate in patients previously diagnosed with endometrial carcinoma. Methodology A retrospective observational study was preformed. Included were patients who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy and pelvic SLN biopsy with or without paraaortocaval biopsy, diagnosed with endometrial carcinoma. SLN mapping was performed with intraoperative cervical indocyanine green (ICG) injection. Basic characteristics were evaluated using descriptive statistics. Surgical data, including number of lymph node retrieved, operative time, and intra/postoperative complication rates, were noted. Results Twenty two patients were included in our study. Mean surgery duration (OR time) was 115.6±37.6 minutes. There were no intraoperative or postoperative complications occurred, as well as ICG injection-related complications. Mean hospital stay was 2.77±1.09 days. Mean number of lymph nodes retrieved was 7±3.9. Two patients (9.09%) had unilateral lymph node metastases. Conclusion We presented a small group of patients who underwent SLN biopsy for endometrial cancer staging. This is the biggest sample of patients where this intervention was preformed in our country. In our experience, laparoscopic SLNB is safe procedure for endometrial carcinoma treatment and staging. Limitations of the study are its retrospective nature and small sample size. Disclosures Authors declare there is no relevant or material financial interests related to research described in this paper.