The use of case studies in college science courses demonstrates the relevance of lecture material and can promote engagement in the classroom. Previously, a group of undergraduates studied the seipin protein and its role in lipid droplet formation as part of a Biomolecular Modeling course. This inspired one of the students, with mentorship from two biochemistry professors, to adapt the knowledge she gained to generate two case studies for use in biochemistry education. The first uses lipid droplet formation to teach students about lipid and membrane biochemistry. The second focuses on protein structure and function of seipin, providing students with an example protein other than hemoglobin and also integrating protein biochemistry with membrane biology. Each case study can be completed in a single class session, but also contains extension activities for further exploration including the utilization of printed 3D models, Alternate Reality (AR) activities, and exploring protein structure using online visualization tools provided by the Protein Data Bank (PDB). The case studies will be made available to those interested in exploring using them.
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Juhler et al. (2024) studied this question.
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