Despite quetiapine is increasingly used 'off-label' in children and adolescents, knowledge on its efficacy and safety is rare and no age-specific therapeutic reference ranges (TRR) have yet been established. The aim of this study was to elucidate whether the TRR described for adults is applicable in minors. Furthermore, the relationship between daily dose, serum concentration and clinical outcome of quetiapine in children and adolescents were investigated.
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Kaiser et al. (2024) studied this question.
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