EUS—A Forgotten Tool for Diagnosing Sarcoidosis

Background: Sarcoidosis is a systemic granulomatous disease, with a predilection for the lung and mediastinal lymph nodes. However, the systemic nature of the disease can lead to diverse manifestations, such as isolated retroperitoneal lymphadenopathy (LN) or intra-abdominal organ involvement. Diagnosis of sarcoidosis is not standardized, but is based on three major criteria: a compatible clinical presentation, the finding of nonnecrotizing granulomatous inflammation in one or more tissue samples, and the exclusion of alternative causes of granulomatous disease. In this study we present the data regarding the role and utility of EUS FNB in patients with suspected sarcoidosis with lymphadenopathy.